The Therapeutic Effect of Domestic Losartan on the Treatment of Reversal Hypertension Left Ventricular Hypertrophy of 60 Cases
- VernacularTitle:国产缬沙坦逆转原发性高血压左心室肥厚60例疗效观察
- Author:
Huiyan ZHAO
- Publication Type:Journal Article
- Keywords:
Losartan;
Primary hypertension;
Left ventricular hypertrophy
- From:
Journal of Medical Research
2006;0(12):-
- CountryChina
- Language:Chinese
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Abstract:
Objective To compare the efficacy and safety of domestic and imported losartan on patients with reversal hypertension left ventricular hypertrophy ( LVH). Methods 118 patients with reversal hypertension left ventricular hypertrophy were randomly divided into two groups. The treatment group of 60 cases were treated by oral domestic losartan and the control group of 58 cases were received oral valsartan imports. The dose was 80mg once day with 6 months for a course of treatment. Before and after treatment, we observed the blood pressure, left ventricular hypertrophy changes in echocardiographic parameters and to monitor the blood, urine routine, liver and kidney function and other indicators,and to record adverse reactions. Results Two groups had lowering blood pressure effect. It was significant difference between before and after treatment( P 0.05 ). Conclusion Domestic and imported valsartan can lower blood pressure in the treatment of reversal hypertension left ventricular hypertrophy, and reverse LVH, without affecting heart rate,and at the same time with fewer adverse reactions.
