Detection of HPV-DNA and SCCAg in the Follow-up of Cervical Squamous Cell Carcinoma Patients
- VernacularTitle:宫颈鳞癌患者随访检测HPV-DNA及SCCAg的临床意义
- Author:
Yu HUANG
;
Qi ZHOU
;
Dong WANG
- Publication Type:Journal Article
- Keywords:
Cervical squamous carcinoma;
Human papilloma virus;
SCCAg;
Prognosis
- From:
Journal of Medical Research
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the infection of human papilloma virus(HPV) and expression of serum squamous cell antigen (SCCAg) in the follow - up of 120 cervical squamous carcinoma patients who had received operation or operation combined with radiotherapy or only radiotherapy. Methods 120 cases of therapical cervical squamous carcinoma patients were detected HPV - DNA by HC - Ⅱ and serum SCCAg using immunohistochemical method. Results The positive rate of HPV - DNA and serum SCCAg was 49.17% and 17.50% , with a significant difference between them( P 0.05 ). Conclusion HPV - DNA test with HC - Ⅱ for follow - up of cervical squamous carcinoma patients was feasible. It was more sensitive than serum SCCAg. But it suggested that high risk type HPV -DNA test combined with serum SCCAg may be the independent prognostic factors.
