Clinical value of human papillomavirus genotype distribution in HPV infection
- VernacularTitle:人乳头瘤病毒亚型在其感染相关疾病中检测的意义
- Author:
Ying JIA
;
Min ZHOU
;
Jin WU
;
Liangdan TANG
- Publication Type:Journal Article
- Keywords:
human papilloma virus;
genotype;
cervix neoplasma;
condyloma;
subclinical infection
- From:Journal of Third Military Medical University
2003;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the distribution of human papillomavirus (HPV) genotype in the diseases associated with HPV infection and explore the role of HPV genotype in these diseases. Methods Retrospective analysis was carried out to compare HPV genotypes of 353 outpatients suffering the diseases associated with HPV infection including cervical caner,cervical intraepithelial neoplasia (CIN),genital duc condyloma,and subclinical cervical human papillomavirus infection (SPI) in our department from January to October 2008. HybriMax were used to detect HPV genotype. The distribution data of HPV genotype were statistically analyzed. Results Totally 176 HPV positive females were found with a positive rate of 49.86%. HPV positive rate in cervical cancer was 100%,and all of them were high risk HPV. The positive rate was increased with the severity of CIN,and the higher histological-grade was,the higher HPV positive rate was (P
