Exploratory analysis about neuroprotection after ischemic stroke
- VernacularTitle:缺血性脑卒中神经保护研究思路的探讨
- Author:
Jiuliang ZHANG
;
Yingzi LI
- Publication Type:Journal Article
- Keywords:
Holism concept ofTCM;
Ischemic stroke;
Penumbra;
Neuroprotection;
Cerebral functional status.
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
To mitigate penumbra injury is the key factor in the treatment ofischemic stroke.Blood reflow and neuroprotection against time are premise to achieve this.Due to time window, thrombolysis rate is low(less than 5% in developed country).However, all neuroprotectants haven't been demonstrated to be effective in human, till now.Based on guidance ofwholism concept ofTCM and analysis ofrelative studies in western medicine.We found that functional status ofnon-ischemic areas can impact on injury degree offocal ischemia.One ofthe reasons that lead to failure in neuroprotective studies may be without considering this impaction.We put forward that non-ischemic areas can impact on the injury degree ofischemic area through the complex neuronal network, and effective regulating the functional status ofnon-ischemic areas is one ofthe key factors which can ameliorate focal ischemic injury.
