Secretory alterations of urethral glands in complete Freund's adjuvant-induced prostatitis in rats
- VernacularTitle:完全弗氏佐剂诱导前列腺炎模型大鼠尿道腺分泌异常的研究
- Author:
Aining WU
;
Enqing XIONG
;
Bo SONG
;
Heng ZHANG
- Publication Type:Journal Article
- Keywords:
prostatitis;
urethral glands;
secretion
- From:Journal of Third Military Medical University
2003;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of prostatitis on secretory alterations of urethral glands in rats.Methods Twenty adult Sprague-Dawley rats were randomly divided into prostatitis group and control group.The prostatitis group(n=10) was injected with 0.1 ml Freund's complete adjuvant at each lateral lobe while the control group(n=10) with 0.1 ml 0.9% physiological saline.Two weeks later the rats were killed and the urethral glands were harvested for pathologic examination and immunohistochemical staining.Results ① There was a great quantity of lymphcells and mononuclear cells infiltrating the prostate gland in prostatitis group while there was no inflammatory cells in control group.② AB-PAS pathologic examination results in urethral glands showed that the grume area,diameter,optical density in control group were significantly less than those of the prostatitis group(P
