Protective effect of Cistanchis glycosides on ethanol-induced liver damage in mice
- VernacularTitle:肉苁蓉总苷对小鼠酒精性肝损伤的保护作用
- Author:
Huiying LUO
;
Yuan LIU
;
Guozhu XI
;
Jiande DU
- Publication Type:Journal Article
- Keywords:
Cistanchis glycosides;
ethanol-induced liver damage;
liver function;
lipid overoxidation reactions
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To research the protection of Cistanchis glycosides on ethanol-induced liver damage in mice.METHODS:40 mice were divided into 4 groups in random,and administered by gavage for 4 weeks.Cistanchis glycosides were twice a day,ethanol were once a day.When time limit arrived,mice were weighted,the serum was afforded to detect the liver function index,liver homogenate were prepared for biochemical detections,liver remained were fixed for pathological investigation.RESULTS:When mice were damaged by ethanol,liver index,liver function index,contents of TG,TC,MDA and LPO were increased distinctly(P
