Progress in drug therapy for retinoblastoma
- VernacularTitle:视网膜母细胞瘤药物治疗进展
- Author:
Han YUE
;
Jiang QIAN
- Publication Type:Journal Article
- Keywords:
retinoblastoma;
drug therapy;
drug deliver system
- From:
Ophthalmology in China
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Retinoblastoma is the most common intraoeular malignant tumor in children.In its treatment,drug therapy is one of the most effective and irreplaceable methods.To reduce the toxicity of drugs,enhance the therapeutic effect and lessen drug resistance, some new drug deliver systems and new medicines for retinoblastoma are coming into being.Ophthalmic arterial infusion,fibrin sealant and iontophoresis are newly-found drug deliver systems.And the latest drugs under research include nutlins,phenoxazine derivative Phx-1,combretastatin A4 phosphate,2-deoxy-d-glucose and histone deacetylase inhibitors,etc.The following text is focused on the two aspects of the drug therapy for retinoblastoma.