The Experimental Study of Liquid Nitrogen Refrigeration Induced Osteonecrosis of the Femeral Head in Rat
- VernacularTitle:液氮冷冻大鼠股骨头坏死的实验研究
- Author:
Xiaoping LIU
;
Al EL
- Publication Type:Journal Article
- Keywords:
Liquid nitrogen freezing;
Rat;
Femoral head;
Avascular necrosis
- From:
Journal of Medical Research
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish animal models of avascular necrosis of the femoral head. Methods Rat models of avascular necrosis of the femoral heads with liquid nitrogen freezing left femoral head were made. After operations, we accessed behaviors and regular observed X - ray graphy. we observed the femoral head after the rats were killed one monthe later. Results The rats in model group presented "new month syndrom" two weeks after operation,and became more and more worse. Conclusion The rat models of avascular necrosis of the femoral heads made by liquid nitrogen is economic and of low mortality. We can use it in making large - scale mordels, particularly in drug treatment' study.
