Effect of Lidan Bushen Granules on acetylcholine and excitatory amino acids of hippocampus in saturnine rats
- VernacularTitle:利胆补肾颗粒对染铅大鼠海马中乙酰胆碱和兴奋性氨基酸的影响
- Author:
Yalei WANG
;
Rong MA
;
Xilian ZHANG
;
Linlin LIU
;
Wenman JIN
- Publication Type:Journal Article
- Keywords:
LiDanBuShen granules;
Children lead poisoning;
Acetylcholine;
Excitatory amino acids
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To discuss the neurobiochemical mechanism of Lidan Bushen Granules in treating saturnine children. Methods: Saturnine rats model was established by intragastric, and was treated with Lidan Bushen Granules for 5 weeks. The acetylcholine and excitatory amino acids of hippocampus in saturnine rats were measured. Results: Compared with the normal group, the ACH and EAA contents of hippocampus in model group rats were dramatically lower (P