Effect of Gengnianle Water-paste Pills on endocrine system of climacteric rat
- VernacularTitle:更年乐水丸对围绝经期造模大鼠内分泌系统的影响
- Author:
Lixia ZHANG
;
Cuiping LI
;
Xia HUANG
;
Yingfei ZHU
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Perimenopausal syndrome;
Gengnianle Water-paste Pills;
Neuroendocrine;
Thyroid gland;
Experiment study
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the mechanism of Gengnianle Water-paste Pills in resisting climacteric aging. Methods: Rats were randomly divided into blank group, model group, high and low dosage groups of Gengnianle, positive control group. The climacteric rat model were established by ectomizing the bilateral ovaries. The E2, follicle-stimulating hormone (FSH), luteinizing hormone (LH), triiodothyronine (T3), thyroid hormone (T4), thyroid-stimulating hormone (TSH) were detected. Results: Compared with model group, in high dose of Gengnianle group, the levels of E2, T3, T4 increased and the levels of FSH, LH, TSH reduced. The effect of high dose of Gengnianle in improving the adjustment function of the thalamus-hypophysis-ovary axis and the thalamus- hypophysis-thyroid gland axis is better than that of positive control group (P
