Postmenopausal osteoporosis in Chongqing region: a risk factors analysis
- VernacularTitle:重庆市绝经后妇女骨质疏松症的危险因素研究
- Author:
Jian WANG
;
Bin WANG
;
Mantian MI
;
Furong SHU
;
Li RAN
;
Jing XU
- Publication Type:Journal Article
- Keywords:
postmenopausal osteoporosis;
bone mineral density;
case control study;
risk factor;
health education
- From:Journal of Third Military Medical University
2003;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of postmenopausal osteoporosis ( PMOP) in Chongqing region,and provide the theoretical basis for osteoporosis prevention and treatment. Methods A hospital-based case-control study was conducted and standardized questionnaire was applied in this project. All patients were informed of the purpose of this study and signed an informed consent form. The protocol and consent form were approved by the Ethics Committee of Third Military Medical University. Non-conditional logistic model was used to estimate the association between risk factors and PMOP. Results After adjustment for some potential confounding factors,multivariate non-conditional logistic regression analysis indicated that family history of hip fracture ( OR = 8. 567,95% CI 3. 463 to 12. 620) ,lower body mass index ( OR = 3. 081,95% CI 1. 344 to 5. 632) ,and parities ( OR = 2. 539,95% CI 1. 263 to 4. 175) were significantly positive correlated with the incidence of PMOP. However,frequently exercise ( OR = 0. 276,95% CI 0. 152 to 0. 730) ,tea drinking ( OR =0. 354,95%CI 0. 209 to 0. 764) and older at menopause ( OR =0. 621,95%CI 0. 327 to 0. 942) were significantly negative correlated with it. Conclusion Family history of hip fracture,lower body mass index and higher parities are the risk factors of PMOP in Chongqing region. Besides,frequent exercise,tea drinking and proper endogenous estrogen level are the protective factors.
