C-type natriuretic peptide:an important effector molecule for renal homeostasis
- VernacularTitle:C型利钠肽:肾脏自稳态平衡的重要效应分子
- Author:
Peng HU
;
Ling LU
;
Bo HU
;
Yuanhan QIN
- Publication Type:Journal Article
- Keywords:
C-type natriuretic peptide;
homeostasis;
kidney;
neutral endopeptidase;
angiotonin;
vascular smooth muscle cell
- From:
Chinese Pharmacological Bulletin
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
C-type natriuretic peptide(CNP),mainly expressed in central nervous system and vascular endothelial cells maintains renal homeostasis by autocrine or paracrine pathway,which regulates water-electrolyte metabolism,vascular resistance,glomerular permeability,and cell proliferation.Thus,clarifying the characteristics of CNP metabolism in kidney would appear promising to develop some new prospects for the evaluation of kidney injury and the targeted therapy.
