Recent developments in purinergic receptors of endocrine pancreas
- VernacularTitle:内分泌胰腺嘌呤受体研究的新进展
- Author:
Guilin LI
;
Shangdong LIANG
- Publication Type:Journal Article
- Keywords:
purinoceptors;
nucleotide;
endocrine pancreas;
secretion of insulin;
diabetes mellitus;
therapeutics
- From:
Chinese Pharmacological Bulletin
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Purinergic receptors are divided into P1(adenosine)and P2(ATP)receptors.P2 receptor are divided into two subtypes,namely P2X(ligand-gated ion channels)and P2Y(G-protein coupled)receptors.Several kinds of purinoceptor subtypes have been expressed in endocrine pancreas and participate in regulating the secretion of insulin.Purinoceptor and ligand are correlated with pathogenesis of diabetes mellitus and complications and make it possible to provide a new target to treat diabetes mellitus and complications.
