The expression of TRAIL in psoriatic patients and healthy subjects
- VernacularTitle:肿瘤坏死因子相关凋亡诱导配体在寻常型银屑病皮肤中的表达
- Author:
Jishun YANG
;
Jianhua WU
;
Quangang ZHU
;
Jiyong LIU
;
Jinhong HU
- Publication Type:Journal Article
- Keywords:
TNF-related apoptosis-inducing ligand;
psoriasis;
skin;
skin lesions;
inflammation;
apoptosis
- From:
Chinese Pharmacological Bulletin
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To explore the expression of TNF-related apoptosis-inducing ligand(TRAIL)between psoriatic patients and healthy subjects.Methods Immunohistochemical staining and Real-Time PCR methods were established to detect the expression of TRAIL.Results Immunohistochemical staining results indicated a significant difference of the expression of TRAIL between psoriatic patients and healthy subjects.Real-Time PCR results indicated that the quantities were 0.42?0.07,1.01?0.16 respectively of two type skins.Thus there were significant differences(P