The Influence of LPS and PDTC on IL -1? Concentration in Endometriai Cell Culture Supernatant.
- VernacularTitle:LPS和PDTC对子宫内膜细胞培养上清液中IL-1?浓度的影响
- Author:
Xiaohong SUN
- Publication Type:Journal Article
- Keywords:
LPS;
PDTC;
Endometriosis;
Endometrial cells;
IL-1?;
NF-?B
- From:
Journal of Medical Research
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To learn the influence of density of LPS and LPS + PDTC on the concentration of IL -1? of endometrial cells. Method We used LPS and LPS + PDTC to intervene normal and endometriosis patients, and obtain cultivate supernatant,then detected the concentration density of IL - 1?with ELISA. Result The of IL - 1? had no statistical signifiance in normal endometrial cells, but there was notable change in eutopic and ectopic endometrial cells. Conclusion Activating and refrainning NF -?B through LPS and PDTC, then decteting the change of the ancentration of IL - 1?, understanding the relation between NF -?B and endometriosis are all important in pathogenesis.
