Clinical Effect Observation of Azithromycin and Ambroxol Hydrochloride in the Treatment of 56 Cases of Children with Acute Lower Respiratory Tract Infection Contraindicating to Penicillin and Cephalosporins.
- VernacularTitle:阿奇霉素、盐酸氨溴索治疗有青霉素及头孢菌素类禁忌的儿童下呼吸道感染56例疗效观察
- Author:
Runchuan FENG
;
Sha LI
;
Xiaoling SONG
- Publication Type:Journal Article
- Keywords:
Azithromycin;
Ambroxol hydrochloride and glucose injection;
Lower respiratory tract infection;
Clinical effect
- From:
Journal of Medical Research
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observate the effects and reliability of azithromycin and ambroxol hydrochloride and glucose Injection in treatment of children with acute lower respiratory tract infection contraindicating to penicillin and cephalosporins. Methods 56 cases of children with acute lower respiratory tract infection for whom penicillin and cephalosporins were treated with azithromycin and ambroxol hydrochloride and glucose injection(group A) and other 100 cases without penicillin and cephalosporins contraindication were randomly divided into group B(treatment with cephalosporin) and group C (treatment with azithromycin). The clinical efficacy and adverse reactions of 3 groups after treatment in children were compared. Results In group A and group B, fever, cough, wheezing and other clinical symptoms, positive signs of the disappearance time of the lung were significantly shorter than those in the group C. The clinical efficacy of the two groups had significant difference as compared with group C (P0.05). Conclusion It is a good treatment with azithromycin and ambroxol hydrochloride and glucose injection to cure children cases with acute lower respiratory tract infection contraindicating to penicillin and cephalosporins, and it' s curative effect is equivalency with cephalosporin. It is worth to use this treatment in clinical practice.