EFFECT OF KONJAC POLYSACCHARIDE ON MOTILIN AND SOMATOSTATIN OF GASTROINTESTINAL TISSUE IN MICE
- VernacularTitle:魔芋多糖对小鼠胃肠组织胃动素与生长抑素的影响
- Author:
Jing JIANG
;
Jinyi ZHONG
;
Jianwei LIN
- Publication Type:Journal Article
- Keywords:
Konjac polysaccharide;
mouse;
motilin;
somatostatin
- From:
Acta Nutrimenta Sinica
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Konjac polysaccharide (KP) on motilin (MOT) and somatostatin (SS) of gastrointestinal tissue in mice. Methods The mice were divided into four groups randomly. Normal control group (NC) was given normal feed. High, middle, low dose KP treated groups (KPH,KPM,KPL)were given KP 0.8, 0.4, 0.2g per 100g normal feed. The level of motilin and somatostatin of gastrointestinal. tissue was determined simultaneously by radioimmunassay, and blood glucose was determined by blood glucose analyzer after 20 d. Body weight, adipose tissue and wet weight of stool were also examined. Results The level of motilin of stools of KPH group was 8.26?0.53ng/g ,which increased compared with NC group.Somatostatin was 207.32?21.89 ng/g ,which decreased compared with NC group. The differences between two groups were significant (P