THE ANTI-TUMOR EFFECT OF THE PROTEOGLYCAN FROM ABALONE VISCERA AGAINST H_(22) CELL LINE IN VIVO
- VernacularTitle:鲍鱼内脏蛋白多糖体内对H_(22)肝癌的抑制作用
- Author:
Lili ZHU
;
Liming SUN
;
Dongmei LI
;
Beiwei ZHU
- Publication Type:Journal Article
- Keywords:
Abalone viscera;
polysaccharide;
antitumor;
immunomodulating
- From:
Acta Nutrimenta Sinica
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the anti-tumor effect of the proteoglycan extracted from abalone viscera (AVPF-I). Methods Hepatic carcinoma cell H22-bearing mice were randomized to negative control (physiological saline), positive control (cyclophosphamide) and three doses of AVPF-I groups. The tumor growth, cell mediated immune function including lymphocyte proliferation, phagocytosis of peritoneal macrophage, NK cell activity, and the level of serum TNF-?,IL-1and IFN-?were detected. Results A significant inhibition of the tumor growth was observed in the AVPF-I group(P
