Superoxide dismutase activity in mice with carrageenan – induced inflammation and influence of some medicinal plants
- Author:
Tran Van Hien
- Publication Type:Journal Article
- Keywords:
Medicinal plants
- MeSH:
Plants, medicinal;
Superoxide Dismutase;
Mice;
Carrageenan;
Inflammation
- From:Journal of Medicinal Materials - Hanoi
2005;10(5):146-149
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Study on oxidant stress status in rat with carrageenan-induced inflammation and intervention’s ability with Artocarpus tonkinensis extract and the aqueous extract (unidentified scientific name), collected in Phu Tho. Results: carragenin 1% injection into sole of the foot of white mice that caused paw edema in mice after 4 hours. The edema status gained medium value of 118.98±15.94mg in sole of the foot. Mivce was preventively administrated by oral diclofenac. Flavonoid extract from Artocarpus tonkinensis leaves and the aqueous extract in studying doses had reduced clearly edema. There were significantly decreases in SOD activities of inflammation mice and increases of MDA level - an indicator of lipid superoxide reaction - in correlation with inflammation status of different mice groups. There was a positive correlation between edema level of mice groups and MDA levels
