Effect and mechanism of protein kinase C ? on cell cycle blockage and apoptosis in human umbilical vein endothelial cells induced by high glucose
- VernacularTitle:蛋白激酶C?在高糖致人脐静脉内皮细胞周期阻滞和凋亡中的作用及机制
- Author:
Fang SUN
;
Bo ZHOU
;
Xuebo LIN
;
Fangfang CHEN
- Publication Type:Journal Article
- Keywords:
protein kinase C-delta;
umbilical veins;
endothelial cells;
glucose;
cell cycle arrest;
apoptosis
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).Again,compared with NG group,the protein expression of PKC? in HUVECs was up-regulated,the cytosol/nuclei ratio of PKC? was decreased,cell cycle was blocked in G0/G1 phase,the apoptosis increased significantly,and the protein content of p-FOXO1(S256) and P27kip1 increased(P
