Role of CYP hypotype on the metabolism of 629 in human liver microsomes in vitro
- VernacularTitle:人肝微粒体CYP亚型在新型吲哚醌类化合物629代谢中的作用
- Author:
Jianghong ZHANG
;
Furong HAO
;
Wensen JIN
;
Zhouhan HU
;
Yizun JIN
- Publication Type:Journal Article
- Keywords:
bioreduction;
629;
human liver microsome;
CYP hypotype;
Metabolism in vitro;
DDI
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusions In human liver microsome system in vitro,CYP1A2,2B6 and CYP2A6 contribute to the metabolism of 629.It is very important for bioreduction drugs design and development,and provide the basic experimental and theoretical profiles for extensive application in clinic.
