Pay close attention to severe adverse effects of tumor necrosis factor blockers
- VernacularTitle:高度关注TNF抑制剂引起严重不良反应的风险
- Author:
Qingtong WANG
;
Wei WEI
- Publication Type:Journal Article
- Keywords:
Tumor necrosis factor blocker;
infliximab;
etanercept;
adalimumab;
adverse effect;
rational administration
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Tumor necrosis factor (TNF) blockers are promising therapeutic agents for patients with conventional therapy insensitive inflammatory diseases.Unfortunately,their use has been associated with an increased rate of malignancies,leukemia,psoriasis and other immune diseases. The U.S. Food and Drug Administration(FDA) is requiring stronger warnings in the prescribing information for TNF blockers. Healthcare Professionals should pay close attention to severe adverse effects of TNF blockers and drug safety.