Role of FOXP3 in tumor immunity
- VernacularTitle:转录因子FOXP3在肿瘤免疫中的作用
- Author:
Lei XUE
;
Zhifei XU
- Publication Type:Journal Article
- Keywords:
forkhead box protein 3;
regulatory T cell;
tumor immunity
- From:
Academic Journal of Second Military Medical University
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
FOXP3,a member of the forkhead/winged-helix family,exerts its immunosupression effect by regulating the development,differentiation and maturation of CD4+ CD25+ regulatory T cells(Treg).Treg plays an important role in immune escape mechanism in oncology research.This article reviews the expression of FOXP3 in various types of tumors and its role in tumor immunology and immunotherapy.
