Experimental Study on the Prevention of Skin Flap Necrosis after Modified Radical Mastectomy in Breast Cancer by Procaine
- VernacularTitle:普鲁卡因干预乳腺癌改良根治术术后皮瓣坏死的实验研究
- Author:
Liang MING
;
Zhaoyong CHEN
;
Xian DING
;
Shumin DONG
;
Min ZHU
- Publication Type:Journal Article
- Keywords:
Procaine;
Breast cancer;
Modified radical mastectomy;
Skin flap necrosis
- From:
Journal of Medical Research
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of procaine on prevention of skin slap necrosis after modified radical mastectomy in breast cancer.Methods 106 breast cancer patients were randomly divided into treatment and control groups.In the treatment group,procaine(1% 100ml diluted in 300ml mormal saline,42℃)were compressed under the skin flap in operation,the control group received same amount of normal salin instead.The rates and sizes of skin flap necrosis were obeserved and compared.Results There were 13 cases suffured from skin flap necrosis among 106 breast cancer cases who received surgery operation.The rate of the flap necrosis in treatment group was5.76%(3/52),and the control group was 18.51%(10/54),there was significant difference(P
