The Clinical Relationship Beteen the Endothelial Dysfunction and Mellitus Retinopathy in the Old Type 2 Diabetes
- VernacularTitle:2型糖尿病老年患者视网膜微血管病变与内皮功能紊乱关系初步探讨
- Author:
Wenwen MAO
;
Zhenglei SHEN
;
Weimeng TIAN
;
Guoqiang CHEN
;
Ning ZHOU
- Publication Type:Journal Article
- Keywords:
Diabetic mellitus;
Micro-blood vessel pathological changes of retinopathy;
Endothelial dysfunction;
FCM
- From:
Journal of Medical Research
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The changes of CECs,EPCs and CPCs in the old type 2 diabetes mellitus retinopathy(DR)patients and the clinical purpose were discussed.Methods 30 cases of T2DM(including 10 DM cases without complications and 20 DM cases with retinopathy)and 10 cases of health controls were enrolled in this study.Results(1)The changes of CECs in DR Patients were significantly higher while the levels of EPCs and CPCs were significantly lower than those in the patients of the control group.(2)There were some corrlation beteen the level of CECs,EPCs and CPCs and the degree of diabetic retinopathy.(3)The serum EPCs levels in type 2 diabetics were negativey associated with body mass index,waist-hip ratio,abdominal circumference,FPG,triglyceride,UAER,creatinine.Conclusion The levels of EPCs and CPCs in T2DM-DR patients may be the important detected targets for early discovery and monitoring of DR.
