Relationship of the sensitivity of colon carcinoma cells to gefitinib and the expressions of MET,IGFR-1? and IGF-Ⅱ
- VernacularTitle:结肠癌细胞对吉非替尼的敏感性与MET和IGFR-1?及其配体IGF-Ⅱ的关系
- Author:
Li YANG
;
Feng PAN
;
Jianjun LI
;
Houjie LIANG
- Publication Type:Journal Article
- Keywords:
colonic neoplasms;
cell line;
gefitinib;
hepatocyte growth factor receptor;
insulin-like growth factor receptor-1;
insulin-like growth factor Ⅱ
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).IGFR-1? expressed in all the 6 cell lines,with the highest expression in SW480(P0.05),but a gefitinib-induced and dose-dependent increase in p-IGFR-1?,not IGFR-1?,expression was observed in HT29 cells(P0.05),but the expression of IGFR-1? was higher in HCT116 than in Lovo and HT29(P
