Antibiotics combined with azithromycin can reduce the drug resistant mutants of pseudomonas aeruginosa in vitro
- VernacularTitle:阿奇霉素与其他抗菌药物联用减少铜绿假单胞菌耐药突变体的研究
- Author:
Mingtao LIU
;
Ruicong YU
;
Enhua SUN
;
Shaojie BI
;
Yu LI
- Publication Type:Journal Article
- Keywords:
azithromycin;
pseudomonas aeruginosa;
selective index
- From:
Chinese Journal of Practical Internal Medicine
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
32,16,16.Combined with azithromycin were8,16,16,8.MEM,CAZ,CIP combined with AMK were 1,4,8.AMK combined with CIP were 4.Conclusion Compared with sole,MEM,CAZ,CIP combined with azithromycin can reduce the MPC and SI of antibiotics alone to pseudomonas aeruginosa and restrain the drug-resistant mutants.But the capacity of preventing mutants arise were weaker than combined with AMK.AMK combined with azithromycin can't reduce the SI.But when combined with CIP,the SI of AMK were reduced greatly.
