A Case of Cowden Syndrome Associated with Tumor of the Follicular Infundibulum.
- Author:
Chan Ho NA
1
;
Yoon Soo KIM
;
Bongseok SHIN
;
Minsung KIM
Author Information
1. Department of Dermatology, Chosun University Medical School, Gwangju, Korea. lier001@naver.com
- Publication Type:Case Report
- Keywords:
Cowden syndrome;
Hereditary condition;
Tumor of the follicular Infundibulum
- MeSH:
Adult;
Biopsy;
Breast Neoplasms;
Endometrial Neoplasms;
Epidermis;
Fathers;
Female;
Foot;
Hamartoma;
Hamartoma Syndrome, Multiple*;
Hand;
Humans;
Mouth;
Pituitary Gland*;
Thyroid Neoplasms;
Thyroid Nodule;
Warts;
Wills
- From:Korean Journal of Dermatology
2016;54(8):650-652
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cowden Syndrome (CS) is a rare genodermatosis of autosomal-dominant inheritance, with variable expressivity and multiple types of hamartomas. The most consistent features of CS are small wart-like papillomatous papules on the face, hands, and mouth. A 31-year-old woman presented with a history of pearly papules on the face, hand, and foot for several years. The lesions were initially diagnosed as warts, and treated accordingly, but they did not subside. There was a history of endometrial cancer, breast cancer, and thyroid nodule, and her father had a history of thyroid cancer. A biopsy specimen from the facial papule showed plate-like growth of anastomosing epithelial cords, extending parallel to the epidermis. It was diagnosed as a tumor of the follicular infundibulum (TFI). The patient refused further treatment. Here, we report a rare case of CS presenting with TFI.
