The application of PK/PD theory in the treatment of respiratory tract infection
- VernacularTitle:药代动力学/药效学理论在呼吸道感染治疗中的应用
- Author:
Rui WANG
- Publication Type:Journal Article
- Keywords:
antibiotics;
pharmacokinetics;
pharmacodynamics;
mutant prevention concentration
- From:
Chinese Journal of Practical Internal Medicine
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
MIC,according to which,the antibiotics frequently used for treating respiratory infections were divided into three groups:Time-dependent(with minimal or no PAE),Concentration-dependent(with PAE),Time-dependent and Concentration-enhanced(with PAE),In addition,the most appropriate antibiotic administration methods are also explored respectively in the article.Finally,several measures of preventing emergence of resistance are proposed based on the theory of MPC.