Research progress of pharmacotherapy on delayed cerebral vasospasm after subarachnoid hemorrhage
- VernacularTitle:药物治疗蛛网膜下腔出血后迟发性脑血管痉挛研究进展
- Author:
Fangling XIONG
;
Yilu GAO
- Publication Type:Journal Article
- Keywords:
subarachnoid hemorrhage;
delayed cerebral vasospasm;
pharmacotherapy
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Delayed cerebral vasospasm (DCVS) is an important incapacitating or lethal cause after subarachnoid hemorrhage (SAH),but the patho-physiological process was vague. The effective drugs of treating DCVS are particularly important including ion channel blockers or openers,endothelin synthetic inhibitor or receptor antagonist,anti-inflammatory agents,antioxidants,fibrinolytic agents,traditional Chinese herbs,etc. The article reviews the research progress in the preclinical and clinical pharmacotherapy on DCVS after SAH,and explores the applications and effects and debates about these therapeutic drugs at present.
