Expressions of Livin ? and Livin ? in marrow mononuclear cells of childhood acute leukemia and the clinical significance
- VernacularTitle:Livin?和Livin?在儿童急性白血病骨髓单个核细胞中的表达及临床意义
- Author:
Chenggang MAO
;
Yuexin GUO
;
Qing LUO
;
Youhua XU
- Publication Type:Journal Article
- Keywords:
Livin;
IAP;
acute leukemia;
children
- From:Journal of Third Military Medical University
2003;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expressions of Livin ? and Livin ? in marrow mononuclear cells(MMNCs)of childhood acute leukemia(CAL)and explore the clinical significance.Methods Real-time quantitative PCR and Western blot were used to detect the mRNA and protein expressions of Livin ? and Livin ? in MMNCs of CAL,respectively.Results Both Livin? and Livin? expression rates and expression levels were higher in preliminary diagnosis group(n=51)of CAL,including acute lymphoblastic leukemia(n=39)and acute myeloid leukemia(n=12),compared with the control group(P5%)to induction chemotherapy of ALL than in the patients without chemotherapy(P
