Pharmacological effects of Silymarin extracted from introduced milk thistle fruits (Silybum marianum (L.) Gaertn.)
- Author:
Trinh Thi Diep
- Publication Type:Journal Article
- Keywords:
milk thistle fruit
- MeSH:
Silymarin;
Fruit;
Pharmacology
- From:Journal of Medicinal Materials - Hanoi
2005;10(5):142-146
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Study on the pharmacological effects of Silymarin extracted from introduced milk thistle fruits (Silybum marianum (L.)) collected at Sa Pa and Ha Noi in June 2002. Results: the silymarin product had chronic anti-inflammatory effects in experimental tumor model, inhibited formation of granuloma with the rate of 28.69% compared with control rats; had hepatic protection effect, decreased GPT enzyme activity and serum bilirubine of rats with 36.19% and 38.18%, respectively, in CCl4 poisoned model compared with control rats; increased bile flow up 32.25% compared with this before receiving silymarin and 49.88% compared with rats without drug, but didn’t change the bile quality
