Role of transient receptor potential vanilloid 1 channel in pancreatitis
- VernacularTitle:瞬时受体电位香草酸亚型1(TRPV1)在胰腺炎中的作用
- Author:
Xingzhi LIAO
;
Hua XU
;
Yuanchang XIONG
- Publication Type:Journal Article
- Keywords:
transient receptor potential vanilloid 1;
pancreatitis;
pain
- From:
Academic Journal of Second Military Medical University
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel,which can be activated by multiple pathways during the course of the diseases.Recent studies indicate that primary sensory neurons of the pancreas express TRPV1 receptor and the activation of TRPV1 receptor promotes pancreatic inflammation.Moreover,blockade of these transient receptor potential channels can greatly ameliorate the pain response in experimental pancreatitis.
