Effect of Aging on the Performance of the Radial Six-arm Water Maze Task in C57BL/6 Mice
- VernacularTitle:年龄对C57BL/6小鼠在辐射状六臂水迷宫中表现的影响
- Author:
Xiangdong XIONG
;
Guihai CHEN
- Publication Type:Journal Article
- Keywords:
Behavior;
Memory;
Mouse;
Aging
- From:
Journal of Medical Research
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore whether there is the decline of learning and memory ability in C57BL/6 mice in radial six-arm water maze (RAWM) task. Methods The RAWM task was used to test the spatial abilities of learning and memory. Results All of old mice showed the decline of spatial learning and memory ability in the RAWM task. Conclusion RAWM task is excellent spatial learning and memory task and is sensitive to measure the age-related decline of learning and memory ability in C57BL/6 mice.
