Correlation of High-Risk Human Papillomavirus with Prognosis of Ovarian Carcinomas
- VernacularTitle:卵巢癌中高危型人乳头瘤病毒感染与预后的关系
- Author:
Qingyang BAI
;
Wei RONG
;
Yurong SUN
- Publication Type:Journal Article
- Keywords:
Ovarian carcinomas;
High-risk human papilloma virus(HPV);
VEGF;
ki-67;
In situ hybridization
- From:
Journal of Medical Research
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relation ship between the high-risk human papillomavirus(HPV) and prognosis of ovarian carcinomas.Methods In situ hybridization technique was used to examine HPV16/18 DNA in 32 cases of benign ovarian epithelial tumors,25 cases of borderline tumors and 45 cases of ovarian carcinoma.Immunohistochemistry was used to examine the expression of VEGF and ki-67 protein,which compared to usual ovarian tissues. Results (1)The positive rate of HPV16/18 was significantly different between ovarian carcinoma and normal epithelial ovarian tissues or benign epithelial ovarian tumors(P
