The expression and meaning of liver X receptor in obstructive sleep apnea-hypopnea syndrome patients
- VernacularTitle:肝X受体在阻塞性睡眠呼吸暂停低通气综合征的表达及意义
- Author:
Yongjie QI
;
Meijuan XU
;
Qin YU
- Publication Type:Journal Article
- Keywords:
sleep apnea;
macrophages;
liver X receptor;
cyclooxygenase-2 cholesterol lipid transporter
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the liver X receptor(LXR)and the gene expression of cholesterol ester transfer protein(CETP),cyclooxygenase-2(COX2)in obstructive sleep apnea hypopnea syndrome(OSAHS)patients.Methods Macrophages were separated from the blood drawn in 30 cases of OSAHS patients and 30 healthy control subjects in the morning,RT-PCR gel eletrophoresis was used to determine the patterns of gene expression.Results OSAHS patients had higher LXR,COX2,CETP expression(P
