Natural history of chronic hepatitis B:advances in clinical practice
- VernacularTitle:慢性乙型肝炎自然史研究进展
- Author:
Sheng JIN
- Publication Type:Journal Article
- Keywords:
hepatitis B virus;
hepatitis B
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
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Abstract:
With several new and effective antiviral agents had been evaluated and licensed in past ten years,natural history of chronic hepatitis B(CHB)has being affected fiercely.But up to now,chronic hepatitis B virus infection is still the most important etiopathogenisis of cirrhosis and hepatocellular carcinoma.Chronic heaptitis B is a dynamic process.The natural history of CHB can be schematically divided into five phases:immune tolerant phase,immune reactive phase,inactive HBV carrier state,HBeAg-nagative CHB,and HBsAg-nagative phase,which are not necessarily sequential.So correct prehension of the natural history of CHB is significant for the prevention,monitoring and appropriate treatment of CHB patients.
