Research progress on traditional Chinese medicine affecting the metabolism of cytochrome P450
- VernacularTitle:中药对细胞色素P450代谢影响的研究进展
- Author:
Ruifang XIE
;
Xin ZHOU
- Publication Type:Journal Article
- Keywords:
traditional Chinese medicine;
CYP;
research in progress
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2002;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Cytochrome P450 is one of the microsomal mixed function oxidase,and plays an important role in the metabolism of exogenous and endogenous material.Lots of domestic and overseas relative literatures were red,the article summarized the research progress of traditional Chinese medicine affecting the metabolism of CYP in recent years.Eight main drug-metabolizing enzymes were respectively introduced,including CYP1A1,CYP1A2,CYP2A6,CYP2C,CYP2D6,CYP2E1,CYP3A4 and CYP3A4.It is important to research CYP450 for drug screening,individual administration.
