The role of protein kinase C in cancer and the progress of inhibitors targeting protein kinase C
- VernacularTitle:蛋白激酶C在肿瘤中的作用及其抑制剂研究进展
- Author:
Li LI
;
Jing LI
;
Meiyu GENG
- Publication Type:Journal Article
- Keywords:
protein kinase C;
inhibitor;
tumor;
signaling transduction
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Protein Kinase C(PKC) plays a key role in carcinogenesis and metastasis,therefore,PKC is the potential molecular target to develop the treatments of cancer.Currently several PKC inhibitors have entered the clinical research stage,at the same time they also bring new challenges to research and development of anti-cancer drugs targeting PKC.The article will review the recent role of PKC in cancer and the progress of inhibitors targeting PKC.
