The Depressant Effect on Lewis Lung Carcinoma and the Effect on the Expression of VEGF by Melting Agent of Anti-lung Cancer(MAALC)
- VernacularTitle:抗肺癌合剂对Lewis肺癌的抑制作用及VEGF表达的影响
- Author:
Minghua WU
;
Weishun ZHOU
;
Changsheng XIE
- Publication Type:Journal Article
- Keywords:
lung neoplasms;
VEGF;
TCM therapy
- From:
Journal of Zhejiang Chinese Medical University
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To study the effect on the growth of mouse Lewis lung carcinoma and on the expression of VEGF in tumor tissue.[Methods] C57BL/6 mice were inoculated the Lewis lung carcinoma cell at right armpit and divided into groups.Different groups were administered by MAALC(low,normal and high dose),CTX or saline.After 15 days,all mice were put to death to detach the tumors then weighed them.After that,we treated tumor tissue with VEGF immunohistochemistry stain,detected the integral optical density of VEGF expression with image analytical technique.[Results] Compared with model group,the average weight and VEGF expression level of the tumors of the high dose group were less and statistically significant(P
