The Effect of Ferrous Glycine Sulfate in Rat Iron-deficiency Anemia Model
- VernacularTitle:甘氨酸亚铁对大鼠缺铁性贫血模型的影响
- Author:
Ke DING
;
Zhengrong ZHAO
;
Xuxiang ZHU
- Publication Type:Journal Article
- Keywords:
Ferrous Glycine Sulfate;
FeSO4 preparation;
iron-deficiency anemia model
- From:
Journal of Zhejiang Chinese Medical University
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To synthesize an amino acid coordinately compounds-Ferrous Glycine Sulfate(FeGly2) using Fe2+ as central iron and study the effect of blood enrichment.[Method]To synthesize the chelate iron using glycin and Fe2+ and measure the constructor of Ferrous Glycine Sulfate by IR spectrum and atomic absorption spectroscopy.To observe the blood enrichment effect of FeGly2 by rat anemia model.[Result] After separately treatment with 200 mg/kg FeGly2 and 300 mg/kg FeSO4 by intragastric administration,the haemoglobin in blood of hypoferric anemia rat increased obviously(P