The effect of Feixian Fang treating the idiopathic pulmonary fibrosis patients in MMPs and TIMPs
- VernacularTitle:肺纤方对特发性肺间质纤维化患者血清基质金属蛋白酶1、2及其抑制剂的影响
- Author:
Xiaomei ZHANG
;
Liangduo JIANG
;
Ting YIN
;
Wei ZHANG
;
Jianjun WU
- Publication Type:Journal Article
- Keywords:
IPF;
Feixian-Fang;
MMP-1;
MMP-2;
TIMP-1;
TIMP-2
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To research the therapeutic effect dnd pulmonary ground substance rebuilding in the treatment on IPF patients by Feixian-Fang and.Methods:Treatment 20 cases IPF by Feixian Fang RCT prednisone three months.obsive The therapeutic efficacy and the levels of matrix met alloproteinase 1,2,tissue inhibtor of met alloproteinase(TIMP-1,2).Results: The total effective rate of Feixian-Fang group is 84.2%.The total effective rate of prednisone group is 81.3%.Feixian-Fang can reduce the level of MMP-1,MMP-2,TIMP-1,TIMP-2 in the serum.Concluds:Feixian-Fang can treat IPF probably through inhibiting pulmonary ground substance rebuilding.
