Effect of the acupoint catgut embedding and Chinese materia medica on leptin and HPGA of castrated rats
- VernacularTitle:穴位埋线及中药对去势肥胖大鼠瘦素与下丘脑-垂体-性腺轴的影响
- Author:
Xiaoguang LUO
;
Nengxian LUO
;
Ming JIANG
;
Qin CHEN
;
Jin HUANG
;
Qin YANG
- Publication Type:Journal Article
- Keywords:
Post-menopause obesity;
Acupoint catgut embedding;
Leptin;
NPY;
HPGA
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of the acupoint catgut embedding and the traditional Chinese medicine on leptin and NPY of castrated rats and the regulating action of the both treatments to HPGA.Methods:To copy castration model by cutting double ovaries of female adult rats,then divide them into groups,after treatments,to observe the weights of castration rats,Lee's index,abdominal cavity fat content and wet weight,serum E 2 ,FSH,Leptin,NPY,GnRH,the number of OB-R positive cells and the change of fatty cells'counting.Results:After treatment,obesity indexes of the each group were unevenly decreased. The level of LP,NPY,GnRH,FSH decreased;the level of E 2 and the number of OB-R positive cells increased.Conclusion:The treatment of the acupoint catgut embedding and TCM can improve the imbalance of HPGA,Leptin resistance and have the effect of losing of weight as well.
