Effects of Yiqi Huoxue Huayu Chinese medicine on expression of bFGF and neogenesis of blood vessels in BPH rats
- VernacularTitle:益气活血化瘀中药对大鼠前列腺增生组织血管新生及bFGF表达的影响
- Author:
Xin YANG
;
Yonghua ZHANG
;
Caifei DING
;
Zhizhong YAN
;
Weidong NI
- Publication Type:Journal Article
- Keywords:
BPH;
Rat;
Neogenesis of blood vessels;
bFGF;
Yiqi Huoxue Huayu
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of Yiqi Huoxue Huayu Chinese medicine on neogenesis of blood vessels and basic fibroblast growth factor(bFGF)expression in benign prostatic hyperplasia(BPH)rats.Methods:7 days after being castrated,fifty SD rats were injected with testosterone(5 mg?kg-1?d-1),the decoction of Yiqi Huoxue Huayu and Zerguilongshuang were orally administrated respectively,after 30 days'treatment,the rats were sacrificed,the prostate volume were measured,and the prostate index(PI)were analyzed,the micro-vessels density(MVD)and level of bFGF were measured.Results:The prostate volume and index of rats in model group was obviously higher than those in normal group(P
