Thromboembolism and anticoagulant therapy in patients with lupus nephritis
- VernacularTitle:狼疮性肾炎合并血栓栓塞与抗凝治疗
- Author:
Xuefeng SUN
;
Jinhuan SU
- Publication Type:Journal Article
- Keywords:
lupus nephritis;
thromboembolism;
anticoagulant therapy
- From:
Chinese Journal of Practical Internal Medicine
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Patients with systemic lupus erythematosus,especially lupus nephritis,are often accompanied by arterial and venous thrombus at various sites.Thrombosis is associated with the extrinsic and intrinsic coagulation pathway activated by inflammation and endothelium injury.Anticoagulant therapy can interrupt the cycle between inflammation and thrombus,which not only prevents and treats the thrombotic disease but also lessens the inflammatory reaction in kidney and attenuates the renal injury.