Changes of tear lipid layer and treatment of evaporative dry eye
- VernacularTitle:蒸发过强型干眼的泪膜脂质层成分变化及治疗策略
- Author:
Jianan ZHANG
;
Xiaoming YAN
- Publication Type:Journal Article
- Keywords:
evaporative dry eye;
tear film;
lipid layer;
therapy
- From:Ophthalmology in China
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The preocular tear film has recently been described as a bilaminar structure,including lipid layer and aqueous/mucin gel layer.The lipid layer has two phases,a relatively thick outer layer,containing nonpolar lipids such as wax esters,sterol esters,hydrocarbons, and triglycerides;and a thin polar inner layer,predominantly consisting of phospholipids.It s confirmed that there are differences in meibomian fatty acid composition between healthy and evaporative dry eye patients.Thus,therapies targeted at replenishing or stabilizing the lipid layer are key points to the treatment of evaporative dry eye,either as monotherapy or in conjunction with therapies designed to enhance aqueous production.
