Research progress in differentiation of embryonic stem cells to hemangioblast
10.3760/cma.j.issn.1673-4181.2009.05.010
- VernacularTitle:胚胎干细胞体外诱导分化为成血管血液干细胞的研究进展
- Author:
Jinxin XUE
;
Wenjie ZHANG
- Publication Type:Journal Article
- Keywords:
Embryonic stem cell;
Hemangioblast;
Differentiation
- From:
International Journal of Biomedical Engineering
2009;32(5):295-298,后插2
- CountryChina
- Language:Chinese
-
Abstract:
The concept of hemangioblast was proposed a century ago. The existence of hemangioblasts has been demonstrated recently in vitro by differentiation of mouse and human embryonic stem (ES) cell into em-bryoid bodies(EBs). In the developing embryo, a common progenitor, termed "hemangioblast", generates both hematopoietic and endothelial cell lineages. The in vitro differentiation of embryonic stem cells to hemangioblast is a powerful approach for studying the commitment of the hematopoietic and endothelial lineages. This review will summarize recent development in the studies on hemangioblast.
