Expressions of cyclooxygenase-2 and epidermal growth factor receptor in transitional cell carcinoma of bladder and their correlation
- VernacularTitle:COX-2和EGFR在膀胱移行细胞癌组织中的表达及其相关性研究
- Author:
Ping LIANG
;
Fengshuo JIN
;
Gang WU
;
Zengpeng LI
;
Qinhong ZHANG
;
Li LIN
- Publication Type:Journal Article
- Keywords:
bladder transitional cell carcinoma;
cyclooxygenase-2;
epidermal growth factor receptor;
immunohistochemistry
- From:Journal of Third Military Medical University
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions and correlation of cyclooxygenase-2 (COX-2) and epidermal growth factor receptor (EGFR) in human transitional cell carcinoma of bladder (TCC) tissues and explore the correlation of their expressions in the incidence and development of TCC. MethodsThe expressions of COX-2 and EGFR were detected by immunohistochemical technique in 48 cases of TCC and in 10 cases of normal bladder mucosa tissues. ResultsThe expressions of COX-2 and EGFR in TCC was significantly higher than those in normal bladder mucosa tissues (P
