The Effect of Kunshen Granule on Angiogenesis Factors(bFGF) of Carcinomatous Rats Experimentally Induced
- VernacularTitle:昆参颗粒对诱导型胃癌大鼠模型血管生成因子(bFGF)的影响
- Author:
Zhiqun CAO
;
Weidong ZH
- Publication Type:Journal Article
- Keywords:
Kunshen Granule;
gastric cancer;
antiangiogenic factors(bFGF);
rats
- From:
Journal of Zhejiang Chinese Medical University
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]Study the principle of Kunshen(KS) Granule in treating progressive gastric carcinoma.[Methods]Oral administration of MNNG to Wister rats resulted in a high incidence of gastric carcinoma.The rats were separated into six groups at random,negative control group,model group,positive control group,Kunshen large dose group,medium dose group and small dose group.Observe the influence of KS Granule in inhibiting the angiogenesis factors bFGF protein level expression of carcinomatous rats organizations experimentally induced,and analyse gray value.[ Result]The angiogenesis factors bFGF of carcinomatous rats experimentally induced were highly expressed.KS Granule can notably decline the expression of protein level.[Conclusion]Kunshen granule can notably inhibit the expression of angiogenesis factors bFGF of carcinomatous rats experimentally induced.
