The Effects of SHENG JI YU HONG Herbs Loading on Modified Gelatin Sponges on Wound Healing by Enhancing Angiogenesis and Improving Granulation Growth
- VernacularTitle:生肌玉红明胶海绵促进机械性创面肉芽生长的实验研究
- Author:
Chang YAO
;
Haijian SUN
;
Yonghui YAO
;
Weiwei GAO
- Publication Type:Journal Article
- Keywords:
SHENG JI YU HONG herbs;
Gelatin sponge;
Angiogenesis;
Wound healing
- From:
Journal of Medical Research
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of SHENG JI YU HONG herbs loading on modified gelatin sponges on the wound healing of mechanical trauma.Methods The round size of 1.8cm diameter of full thickness back skin was cut mechanically and covered with petrolatum gauzes,modified gelatin sponges,SHENG JI YU HONG plasters and SHENG JI YU HONG herbs loading on modified gelatin sponges respectively.On day3,day7 and day14 after model mading,the wound surface healing rate,the amount of hydroxyproline,hemoglobin,the number of capillaries and the cells with positive rhVEGF165 by immunochemical method inside granulation of the wound were detected individually.Results On day3,the wound surface healing rate and the number of capillaries and the cells with positive rhVEGF165 of SHENG JI YU HONG herbs loading on modified gelatin sponges were significant enhanced than those in the other groups.On day14,all the experimental indicators of SHENG JI YU HONG herbs loading on modified gelatin sponges were better than those in the other groups with P
